translated from Spanish: Nobel Prize: how therapy awarded the Nobel Prize in medicine made Jimmy Carter cancer disappear

our own immune system can be a RMA fundamental to fight cancer: that is the premise behind the therapy on Monday awarded the Nobel Prize for medicine 2018.
And it’s a therapy that has at least one very famous patient: the former President of the Estados Unidos Jimmy Carter.
Three years ago, the Uribe who in 2002 received the Nobel Peace Prize, thought that there were only a few weeks of life. “I’m prepared for whatever it is and I hope a new adventure”, said in August, 2015 at a press conference in his native Georgia. “This is in God’s hands.”
James P. Allison and Tasuku Honjo immunologists win the prize Nobel Prize in medicine for discovering how to use our own cells to fight cancer was 90 years old and the doctors had him remove part of liver but had also found four foci of Melanoma of the brain.
However, only four months later, Carter surprised the world with the news that had no trace of cancer in his body.
Immunologists Tasuku Honjo and James P. Allison won Monday the Nobel Medicine Prize for their contribution to the fight against cancer. The democratic USA ruled between 1977 and 1981 had undergone radiotherapy and treatment with pembrolizumab, a drug that prepares the immune system so that it combat tumors. At three months, doctors decided to stop giving it: scanners threw that Carter was free of the disease.
The guardian of the pembrolizumab body is a medicine developed from the discovery of the Japanese Tasuku Honjo, one of Immunologists awarded the Nobel Prize in medicine this year.
Both he and the American James P. Allison studied, each on their own, as a protein serves as a brake to the T lymphocytes, the main cells of our immune system.
What is and how does immunotherapy work, treatment that Jimmy Carter says cured her cancer T lymphocytes are a type of white blood cell that is born in the bone marrow and circulates through our body protective guardian mode. When you find any threat, for example a virus, begins to act to eliminate it.
Honjo discovered that there is a protein, the PD-1, capable of stopping T cell attack that puts us in danger. Allison studied one that fulfills the same function but with a different strategy, CTLA-4, and worked on how use it to combat tumors.
T-lymphocytes through our body for threats. Allison method gives good results against melanoma, although the Honjo is more comprehensive, since it acts against a wider range of cancers including lung or the kidney.
In the case of Carter, the pembrolizumab, which inhibits the PD-1 was used.
Melanoma cancels the ability of T lymphocytes attack, but the pembrolizumab cuts this effect and allows cells to fight the tumor without that protein stop them.
And Jimmy Carter announces that he is cancer-free in addition, medication works as antibody, provoke these immune cells to act.
The pembrolizumab is not the only drug that has emerged from these discoveries awarded with the Nobel Prize. Now there are others that also give hope to those who have advanced cancer and that it was incurable.
Although they do not always work for everyone, but in some patients it has been very effective, eliminating the tumor full even when he had already begun to spread through the body.
Carter is one of them. He not only survived cancer but that today, at the age of 94, he continued with its activity of social support and promotion of democracy through the Carter Center.

Original source in Spanish