translated from Spanish: Pfizer COVID vaccine would be less effective in obese people

USA.- The Pfizer vaccine may be less effective in protecting obese people from coronavirus, scientists said in a study in Italy.Researchers in Rome found that obese people who had received two doses of the vaccine generated a weaker antibody response, according to a report from the Medrxiv prepress server.
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The study, which has not been peer reviewed, evaluated the effect of the vaccine on 248 health workers seven days after the final dose.

Researchers at the Regina Elena National Cancer Institute found that those considered obese, which is defined as having a body mass index (BMI) of more than 30, produced about half the amount of antibodies compared to healthy people. 

Within the study, healthy people have a good acceptance of the drug. Afp

Read more: 14-year-old girl is accused of killing her granny to scoping in MichiganCurrently it is not known what level of antibodies is needed to neutralize the virus, but experts fear that a reduced antibody response could hinder inoculation efforts. The team said their findings highlight important implications in vaccination strategies for obese people.
Since obesity is a significant risk factor for morbidity and mortality for Covid-19 patients, it is mandatory to plan an effective vaccination program in this subgroup, the study authors wrote.

Many other studies link age to the variation in vaccine effectiveness. Afp

Read more: Joe Biden has not contemplated sharing Covid-19 vaccines with Mexico: White HouseA choice that could be considered would be to give them an extra or stronger dose.» Although more studies are needed, this data can have important implications for developing vaccination strategies for Covid-19, particularly in obese people.»

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«If our data were confirmed by larger studies, giving obese people an additional dose of the vaccine or a higher dose could be options to evaluate in this population,» the researchers wrote.

Original source in Spanish

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